Article
Type I cadherins are required for differentiation and coordinated rotation in Xenopus laevis somitogenesis.
The International journal of developmental biology - 1 Sept 2002
Giacomello Emiliana, Vallin Jerome, Morali Olivier, Coulter Ivan S, Boulekbache Habib, Thiery Jean P, Broders Florence
Abstract excerpt
In Xenopus laevis somitogenesis, somitic blocks undergo coordinated movements resulting in their detachment from the rest of the mesodermal ridge, followed by a 90 degrees rotation of the entire metamere. Here we investigated the function of type I cadherins in somitogenesis. Type I cadherins are Ca(2+)-dependent cell-cell adhesion molecules concentrated in the adherens junctions and highly expressed in the...
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