Article
Coordinate regulation of transcription and splicing by steroid receptor coregulators.
Science (New York, N.Y.) - 11 Oct 2002
Auboeuf Didier, Hönig Arnd, Berget Susan M, O'Malley Bert W
Abstract excerpt
Recent observations indicating that promoter identity influences alternative RNA-processing decisions have created interest in the regulatory interactions between RNA polymerase II transcription and precursor messenger RNA (pre-mRNA) processing. We examined the impact of steroid receptor-mediated transcription on RNA processing with reporter genes subject to alternative splicing driven by steroid-sensitive...
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