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Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responses

4 Oct 2002

Abstract excerpt

Hantaviruses cause two human diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantaviruses infect human endothelial cells but cause little or no damage to the infected endothelium. We analyzed with Affymetrix DNA Arrays (Santa Clara, CA) the endothelial cell transcriptional responses directed by hantaviruses associated with HPS [New York-1 virus (NY-1V)], HFRS...

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PMID: 12368479
DOI: 10.1073/pnas.192298899

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