Article
A locus for autosomal dominant keratoconus: linkage to 16q22.3-q23.1 in Finnish families.
Investigative ophthalmology & visual science - 1 Oct 2002
Tyynismaa Henna, Sistonen Pertti, Tuupanen Sari, Tervo Timo, Dammert Anja, Latvala Terho, Alitalo Tiina
Abstract excerpt
PURPOSE: The estimated world-wide prevalence of keratoconus is 50 to 230 per 100,000 in the general population. Sporadic keratoconus is the leading cause of corneal transplantation surgery in Western countries. Positive family history has been reported in 6% to 8% of patients. The purpose of this study was to map the disease locus in 20 Finnish families with autosomal dominant keratoconus, each family having two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.