Article
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma.
Environmental and molecular mutagenesis - 1 Jan 2002
Gontijo Alisson Marques de Miranda Cabral, Marcondes João Paulo de Castro, Elias Flávia Nunes, de Oliveira Maria Luiza Cotrim Sartor, de Lima Rodrigo Otávio Alves, Salvadori Daisy Maria Favero, de Camargo João Lauro Viana
Abstract excerpt
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay was conducted with cells obtained by urinary bladder washings from 44 patients (28 with a history of previous UCC). Increased DNA damage was observed in cytologically "normal" urothelial cells of...
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