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Article

A BRCA1/2 mutation, high breast density and prominent pushing margins of a tumor independently contribute to a frequent false-negative mammography.

International journal of cancer - 1 Nov 2002

Tilanus-Linthorst Madeleine, Verhoog Leon, Obdeijn Inge-Marie, Bartels Karina, Menke-Pluymers Marian, Eggermont Alexander, Klijn Jan, Meijers-Heijboer Hanne, van der Kwast Theo, Brekelmans Cecile

Abstract excerpt

Female BRCA1/2 mutation carriers develop in up to 50% breast cancer (BC) before age 50 years. We investigated whether the specific histologic features of BRCA1/2-associated breast cancer influence imaging. We correlated the mammographic results with the histology of 34 BC in BRCA1/2 mutation carr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12353239
DOI: 10.1002/ijc.10666

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12353239-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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