Article
Investigation on genetic thrombophilic factors in FFPE autopsy tissue from subjects who died from pulmonary embolism.
International journal of legal medicine - 1 Mar 2017
Brandimarti Francesco, Alessandrini Federica, Pesaresi Mauro, Catalani Chiara, De Angelis Letizia, Galeazzi Roberta, Giovagnetti Simona, Gesuita Rosaria, Righi Elisa, Giorgetti Raffaele, Tagliabracci Adriano
Abstract excerpt
Venous thromboembolism (VTE) is a multifactorial disease determined by a combination of inherited and acquired factors. Inherited factors include mutations in the genes coding for coagulation factors, some of which seem to exert a differential influence on the risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE). In post-mortem studies of subjects who have died from pulmonary embolism (PE),...
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