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The role of cholesterol efflux in regulating the fertilization potential of mammalian spermatozoa

15 Sept 2002

Abstract excerpt

Following spermatogenesis and spermiogenesis, mammalian spermatozoa leaving the testis appear to be morphologically mature but clearly are immature from a functional standpoint; that is, they have acquired neither progressive motility nor the ability to fertilize a metaphase II‐arrested egg. Although progressive motility is acquired and signaling pathways mature during sperm transit through the epididymis,...

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Share to Lipid metabolism and biosynthesis
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

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PMID: 12235100
DOI: 10.1172/jci16392

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