Mouse-human orthology relationships in an olfactory receptor gene cluster.

doi:10.1006/geno.2000.6431

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Article

Mouse-human orthology relationships in an olfactory receptor gene cluster.

Genomics - 1 Feb 2001

Lapidot M, Pilpel Y, Gilad Y, Falcovitz A, Sharon D, Haaf T, Lancet D

Abstract excerpt

The olfactory receptor (OR) subgenome harbors the largest known gene family in mammals, disposed in clusters on numerous chromosomes. One of the best characterized OR clusters, located at human chromosome 17p13.3, has previously been studied by us in human and in other primates, revealing a conserved set of 17 OR genes. Here, we report the identification of a syntenic OR cluster in the mouse and the partial DNA...

Topics

Animals
Chromosomes
Chromosomes, Human, Pair 17
Cloning, Molecular
Conserved Sequence
Evolution, Molecular
Gene Library
Genome
Humans
In Situ Hybridization
In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Models, Biological

Models, Genetic

Molecular Sequence Data

Multigene Family

Phenotype

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 11170746
DOI: 10.1006/geno.2000.6431

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