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Article

Balanced X chromosome inactivation patterns in the Rett syndrome brain.

American journal of medical genetics - 1 Aug 2002

Shahbazian Mona D, Sun Yaling, Zoghbi Huda Y

Abstract excerpt

In Rett syndrome (RTT), an X-linked disorder essentially limited to females, neurological development goes awry. Causing this disarray in neuronal function is a mutated form of a protein known as methyl-CpG-binding protein 2 (MeCP2). Because the MECP2 gene is subject to X chromosome inactivation (XCI) in females, a number of studies have addressed whether the percentage of cells inactivating the normal vs. mutant...

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Source

Identifiers

PMID: 12210344
DOI: 10.1002/ajmg.10557

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Balanced X chromosome inactivation patterns in the Rett syndrome brain.PMID 12210344Read ↗

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