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Article

X chromosome inactivation patterns in brain in Rett syndrome: implications for the disease phenotype.

Brain & development - 1 Jun 2005

Gibson Joanne H, Williamson Sarah L, Arbuckle Susan, Christodoulou John

Abstract excerpt

Skewed X chromosome inactivation (XCI) has been implicated in modulating the severity of Rett syndrome (RTT), although studies by different groups have yielded conflicting results. In this study we have characterised the XCI pattern in various neuroanatomical regions of nine RTT brains and non-neural tissue in two of these patients to determine whether or not variable XCI patterns occur in different brain regions...

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Source

Identifiers

PMID: 15862188
DOI: 10.1016/j.braindev.2004.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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X chromosome inactivation patterns in brain in Rett syndrome: implications for the disease phenotype.PMID 15862188Read ↗

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