Article
High-throughput behavioral screening method for detecting auditory response defects in zebrafish.
Journal of neuroscience methods - 30 Aug 2002
Bang Pascal I, Yelick Pamela C, Malicki Jarema J, Sewell William F
Abstract excerpt
We have developed an automated, high-throughput behavioral screening method for detecting hearing defects in zebrafish. Our assay monitors a rapid escape reflex in response to a loud sound. With this approach, 36 adult zebrafish, restrained in visually isolated compartments, can be simultaneously assessed for responsiveness to near-field 400 Hz sinusoidal tone bursts. Automated, objective determinations of...
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