[Cardiovascular pathology of Marfan syndrome].

Abstract excerpt

In Marfan syndrome, mutations of the fibrillin gene lead to various cardiovascular lesions, such as aortic root dilatation, aortic dissection, and floppy mitral or aortic valve. Disorganization and fragmentation of elastic fibers, characteristic histologic findings of cardiac valves and aortas in Marfan syndrome, are similar to the changes of elastic fibers in non-Marfan dissected aortas and idiopathic floppy...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aorta
• Share to Cardiovascular System
• Share to Fibrillins