Article
Impact of topotecan-based chemotherapy on the immune system of advanced ovarian cancer patients: an immunophenotypic study.
Oncology reports - 1 Jan 2000
Ferrari Silvia, Rovati Bianca, Cucca Lucia, Scarabelli Claudio, Presti Mauro, Beccaria Cristina, Collovà Elena, Porta Camillo, Danova Marco
Abstract excerpt
The effects of topotecan-based chemotherapy (CT) on peripheral blood lymphocyte (PBL) subsets were evaluated in ovarian cancer patients. Fourteen patients with epithelial ovarian cancer, at the diagnosis or relapsed after platinum-based CT, were treated with: a) topotecan in association with carboplatin and taxanes as first line CT; b) topotecan alone or c) topotecan in association with carboplatin both as second...
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