Article
Impact of topotecan-based chemotherapy on the immune system of advanced ovarian cancer patients: an immunophenotypic study.
Oncology reports - 1 Jan 2000
Ferrari Silvia, Rovati Bianca, Cucca Lucia, Scarabelli Claudio, Presti Mauro, Beccaria Cristina, Collovà Elena, Porta Camillo, Danova Marco
Abstract excerpt
The effects of topotecan-based chemotherapy (CT) on peripheral blood lymphocyte (PBL) subsets were evaluated in ovarian cancer patients. Fourteen patients with epithelial ovarian cancer, at the diagnosis or relapsed after platinum-based CT, were treated with: a) topotecan in association with carboplatin and taxanes as first line CT; b) topotecan alone or c) topotecan in association with carboplatin both as second...
Topics
- Adult
- Aged
- Antineoplastic Agents
- Female
- Humans
- Immune System
- Immunologic Memory
- Immunophenotyping
- Lymphocyte Subsets
- Middle Aged
- Ovarian Neoplasms
- Phenotype
- Recurrence
- Time Factors
