Article
The NorR protein of Escherichia coli activates expression of the flavorubredoxin gene norV in response to reactive nitrogen species.
Journal of bacteriology - 1 Aug 2002
Hutchings Matthew I, Mandhana Neeraj, Spiro Stephen
Abstract excerpt
The Escherichia coli norVW genes encode a flavorubredoxin and NADH:(flavo)rubredoxin reductase, respectively, which are involved in nitric oxide detoxification under anaerobic growth conditions. Here it is shown that the norVW genes also have a role in protection against reactive nitrogen intermediates generated from nitroprusside. Transcription from the norV promoter is activated by the presence of nitroprusside...
Topics
- Base Sequence
- DNA, Intergenic
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Molecular Sequence Data
- NADH, NADPH Oxidoreductases
- Nitric Oxide
- Phenotype
- Promoter Regions, Genetic
- Reactive Nitrogen Species
- Transcription Factors