Article
No major effect of estrogen receptor beta gene RsaI polymorphism on bone mineral density and response to alendronate therapy in postmenopausal osteoporosis.
The Journal of steroid biochemistry and molecular biology - 1 Jun 2002
Arko Barbara, Prezelj Janez, Komel Radovan, Kocijancic Andreja, Marc Janja
Abstract excerpt
Genetic factors play an important role in the pathogenesis of osteoporosis. The genes involved are, however, still largely unknown. In the present study, we have investigated whether sequence variations in the estrogen receptor beta (ERbeta) gene are associated with bone mineral density (BMD) and biochemical markers of bone turnover in 79 Slovenian postmenopausal women with osteoporosis. We also assessed the...
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