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Article

Characterization of SMOC-1, a Novel Modular Calcium-binding Protein in Basement Membranes

1 Oct 2002

Abstract excerpt

We have isolated the novel gene SMOC-1 that encodes a secreted modular protein containing an EF-hand calcium-binding domain homologous to that in BM-40. It further consists of two thyroglobulin-like domains, a follistatin-like domain and a novel domain. Recombinant expression in human cells showed that SMOC-1 is a glycoprotein with a calcium-dependent conformation. Results from Northern blots, reverse...

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PMID: 12130637
DOI: 10.1074/jbc.m203830200

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