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Article

A quantitative trait locus on chromosome 22 for serum leptin levels adjusted for serum testosterone.

Obesity research - 1 Jul 2002

Martin Lisa J, Mahaney Michael C, Almasy Laura, Hixson James E, Cole Shelley A, MacCluer Jean W, Jaquish Cashell E, Blangero John, Comuzzie Anthony G

Abstract excerpt

OBJECTIVE: Studies have reported the existence of marked sexual dimorphism in serum leptin levels in humans with women having approximately two to three times the levels of men. We have shown that this sexual dimorphism has a strong genetic component arising from a genotype by sex interaction, but adjusting leptin levels for testosterone eliminates this interaction. Because interactions such as genotype x sex can...

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Identifiers

PMID: 12105281
DOI: 10.1038/oby.2002.82

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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