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Identification of cytotoxic T lymphocyte epitopes of human herpesvirus 8

27 Jun 2002

Abstract excerpt

The human herpesvirus 8 (HHV-8) is a human gamma2-herpesvirus that is implicated in the development of Kaposi's sarcoma (KS), primary effusion lymphoma and Castelman's disease. Since the responses of cytotoxic T lymphocytes (CTL) play a key role in the control of herpesvirus infection, it is important to identify and to characterize the CTL target epitopes of HHV-8 viral antigens. In this study, using...

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PMID: 12100728
DOI: 10.1046/j.1365-2567.2002.01424.x

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