Vasculogenesis, Angiogenesis and the Molecular Organisation of Endothelial Junctions in the Early Human Placenta

Abstract excerpt

Vasculogenesis and angiogenesis are regulated by the capacity of endothelial cells to adhere to each other and form new tubes. The presence and role of junctional adhesion molecules during physiological vasculogenesis is unknown. Using ultrastructural and immunocytochemical approaches, we compared the junctional phenotype of developing vessels of the first-trimester human placenta with vessels in the last...

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