Article
[Study of the ultrastructural and functional expression of the hepatocyte genome under conditions of prolonged depression of protein biosynthesis by cycloheximide. III].
TSitologiia i genetika - 1 Jan 2000
Galkin A P, Andrianov V M, Mitrokhin Iu I, Todorov I N
Abstract excerpt
Dynamics of changes in mtRNA synthesis and mitochondria ultrastructure is strictly dependent on the level of inhibition of biosynthesis of cytoplasm proteins and "soluble" proteins of mitochondria by cycloheximide in hepatocytes: 1-6 hrs later a progressive weakening of protein synthesis is accom...
Topics
- Animals
- Cycloheximide
- Cytoplasm
- Genotype
- Liver
- Male
- Mitochondria, Liver
- Protein Biosynthesis
- RNA, Messenger
- RNA, Transfer
- Rats
- Time Factors