Article
Relationship between genetic polymorphisms of alcohol-metabolizing enzymes and changes in risk factors for coronary heart disease associated with alcohol consumption.
Clinical chemistry - 1 Jul 2002
Hashimoto Yoshiaki, Nakayama Toshifumi, Futamura Azusa, Omura Miho, Nakarai Hideo, Nakahara Kazuhiko
Abstract excerpt
BACKGROUND: There are large individual variations in the responses of risk factors for coronary heart disease to alcohol consumption. To clarify the factors responsible for these individual variations, we studied the relationship between blood pressure, serum lipids, and uric acid and the genetic polymorphisms of alcohol dehydrogenase (ADH) 2 and aldehyde dehydrogenase (ALDH) 2 in alcohol drinkers. METHODS: We...
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