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Article

The family of toxin‐related ecto‐ADP‐ribosyltransferases in humans and the mouse

1 Jul 2002

Abstract excerpt

ADP-ribosyltransferases including toxins secreted by Vibrio cholera, Pseudomonas aerurginosa, and other pathogenic bacteria inactivate the function of human target proteins by attaching ADP-ribose onto a critical amino acid residue. Cross-species polymerase chain reaction (PCR) and database mining identified the orthologs of these ADP-ribosylating toxins in humans and the mouse. The human genome contains four...

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PMID: 12070318
DOI: 10.1110/ps.0200602

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