Article
Loss of gamma-Catenin expression in squamous differentiation in endometrial carcinomas.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2002
Ashihara Koji, Saito Tsuyoshi, Mizumoto Hisanobu, Adachi Katsuya, Tanaka Ryoichi, Nishimura Makoto, Ito Eiki, Kudo Ryuichi
Abstract excerpt
Squamous differentiation occurs in 25 to 50% of endometrial endometrioid adenocarcinomas. In this study, we analyzed the immunohistochemical expression and localization of beta- and gamma-catenin, molecular changes in the beta-catenin gene, and the subcellular localization of the desmosomal component protein, desmoplakin, by laser scanning microscopy in 35 endometrial carcinomas with squamous differentiation. In...
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