Article
Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa.
Infection and immunity - 1 Jul 2002
Leav Brett A, Mackay Malanie R, Anyanwu Akudo, O' Connor Roberta M, Cevallos Ana Maria, Kindra Gurpreet, Rollins Nigel C, Bennish Michael L, Nelson Richard G, Ward Honorine D
Abstract excerpt
Cryptosporidium sp. is a significant cause of diarrheal disease, particularly in human immunodeficiency virus (HIV)-infected patients in developing countries. We recently cloned and sequenced several alleles of the highly polymorphic single-copy Cryptosporidium parvum gene Cpgp40/15. This gene encodes a precursor protein that is proteolytically cleaved to yield mature cell surface glycoproteins gp40 and gp15,...
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