Molecular Cloning and Expression of a Gene Encoding<i>Cryptosporidium parvum</i>Glycoproteins gp40 and gp15

Abstract excerpt

Cryptosporidium parvum is a significant cause of diarrheal disease worldwide. The specific molecules that mediate C. parvum-host cell interactions and the molecular mechanisms involved in the pathogenesis of cryptosporidiosis are unknown. In this study we have shown that gp40, a mucin-like glycoprotein, is localized to the surface and apical region of invasive stages of the parasite and is shed from its surface....

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