Article
Non-HFE hemochromatosis: genetics, pathogenesis, and clinical management.
Current gastroenterology reports - 1 Feb 2005
Nelson James E, Kowdley Kris V
Abstract excerpt
Recent advances in our understanding of iron metabolism and the epidemiology of iron overload disorders have shown that hereditary forms of hemochromatosis can result from mutations in several iron metabolism genes other than HFE, including Hamp, HJV, TFR2, and SCL40A. These "non-HFE" forms of hemochromatosis are much rarer than HFE-related hemochromatosis but exhibit a similar phenotype, and with the exception...
Topics
- Adolescent
- Adult
- Age Factors
- Child
- Female
- Genetic Predisposition to Disease
- Hemochromatosis
- Hemochromatosis Protein
- Histocompatibility Antigens Class I
- Humans
- Iron
- Iron Metabolism Disorders