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Article

Diversity of benzimidazole-resistance alleles in populations of small ruminant parasites.

International journal for parasitology - 15 Jun 2002

Silvestre A, Humbert J F

Abstract excerpt

The resistance of gastro-intestinal nematodes of small ruminants (sheep and goat) to benzimidazole anthelmintic drugs seems to be linked primarily to a single mutation in the isotype 1 beta-tubulin gene. This study was carried out to investigate the origin and diversity of benzimidazole-resistance alleles in trichostrongylid nematodes. We sequenced a 550 bp fragment of the isotype 1 beta-tubulin gene from several...

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PMID: 12062563
DOI: 10.1016/s0020-7519(02)00032-2

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