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Article

Placement of 19F into the center of GB1: effects on structure and stability.

FEBS letters - 24 Apr 2002

Campos-Olivas Ramón, Aziz Rehan, Helms Gregory L, Evans Jeremy N S, Gronenborn Angela M

Abstract excerpt

A structural and thermodynamic characterization of 5F-Trp-substituted immunoglobulin binding domain B1 of streptococcal protein G (GB1) was carried out by nuclear magnetic resonance and circular dichroism spectroscopy. A single fluorine reporter atom was positioned at the center of the three-dimensional structure, uniquely poised to be exploited for studying interior properties of this protein. We demonstrate...

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Source

Identifiers

PMID: 12062409
DOI: 10.1016/s0014-5793(02)02577-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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