Article
Mutation analysis of the CACNA1A calcium channel subunit gene in 27 patients with sporadic hemiplegic migraine.
Archives of neurology - 1 Jun 2002
Terwindt Gisela, Kors Esther, Haan Joost, Vermeulen Frans, Van den Maagdenberg Arn, Frants Rune, Ferrari Michel
Abstract excerpt
BACKGROUND: Familial hemiplegic migraine is a rare autosomal dominant subtype of migraine with aura that in half of the families is caused by mutations in the CACNA1A gene on chromosome 19p13. In sporadic hemiplegic migraine (SHM), that is, hemiplegic migraine without affected family members, the contribution of the CACNA1A gene is unknown. OBJECTIVE: To investigate the involvement of the CACNA1A calcium channel...
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