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Article

Molecular evolution of the Est-6 gene in Drosophila melanogaster: contrasting patterns of DNA variability in adjacent functional regions.

Gene - 17 Apr 2002

Balakirev Evgeniy S, Balakirev Elena I, Ayala Francisco J

Abstract excerpt

We have investigated nucleotide polymorphism at the esterase 6 gene (Est-6) gene, including the complete coding region (1686 bp), as well as the 5'-flanking (1183 bp) and 3'-flanking (193 bp) regions of the gene, in 30 strains of Drosophila melanogaster and in one strain of Drosophila simulans. The level of silent variation is similar in the coding and in the 3'-flanking region, but smaller in the 5'-flanking...

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PMID: 12034506
DOI: 10.1016/s0378-1119(02)00477-8

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