Article
Interferon and ribavirin as frontline treatment for chronic hepatitis C infection in thalassaemia major.
British journal of haematology - 1 Jun 2002
Li Chi Kong, Chan Paul K S, Ling Siu Cheung, Ha Shau Yin
Abstract excerpt
Hepatitis C virus (HCV) infection is common in transfusion-dependent thalassaemia. The clinical usefulness of 12-month treatment, using interferon alpha 3 MIU/m2 thrice weekly and oral ribavirin 16 mg/kg/d, was evaluated in 18 previously untreated thalassaemia patients. The median age at start of treatment was 16 years (range 7-29). Fourteen were infected with genotype 1b and 4 with genotype 6a. The sustained...
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