Article
Hereditary factors in pancreatic cancer.
Journal of hepato-biliary-pancreatic surgery - 1 Jan 2002
Lynch Henry T, Brand Randall E, Lynch Jane F, Fusaro Ramon M, Kern Scott E
Abstract excerpt
The incidence and the mortality rates for pancreatic cancer are the same, indicating its dismal outlook. Its natural history remains elusive. Cigarette smoking appears to be the most significant environmental culprit. Hereditary factors may account for approximately 5% of the total pancreatic cancer burden. However, when its extant heterogeneity and the reduced penetrance of causal germline mutations are...
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