Article
Familial pancreatic cancer: a review.
Seminars in oncology - 1 Apr 1996
Lynch H T, Smyrk T, Kern S E, Hruban R H, Lightdale C J, Lemon S J, Lynch J F, Fusaro L R, Fusaro R M, Ghadirian P
Abstract excerpt
The cause of pancreatic cancer remains elusive. The most consistently identified epidemiological risk factor is cigarette smoking. Genetic factors are known to play a significant role in perhaps 5% of the total pancreatic cancer burden. Recent discoveries in molecular biology, particularly germline mutations in inherited conditions which feature pancreatic cancer as an integral part of the tumor spectrum such as...
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