Article
An immunogenetic map of Lombardy (Northern Italy).
Annals of human genetics - 1 Jan 2002
Martinetti M, Degioanni A, D'Aronzo A M, Benazzi E, Carpanelli R, Castellani L, Cenzuales S, De Biase U, De Filippo C, De Giuli A, Gerosa A, Faré M, Ferrioli G, Galvani G, Lombardo C, Malagoli A, Marchesi S, Mascaretti L, Motta F, Sioli V, Rinaldini C, Rizzolo L, Pascutto C, Bernardinelli L, Salvaneschi L
Abstract excerpt
For this study we consulted the Bone Marrow Donors' Registry of Lombardy (Italy) and analyzed 43937 HLA-A,B phenotypes and 13922 HLA-A,B,DR phenotypes. We estimated the HLA-A,B and HLA-A,B,DR haplotype frequencies via the maximum-likelihood method. We analyzed the genetic structure of the 11 provinces of Lombardy by means of Principal Component Analysis and Correspondence Analysis, and estimated the variety of...
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