Article
The distribution of HLA antigens in Italy.
Gene geography : a computerized bulletin on human gene frequencies - 1 Jan 2000
Piazza A, Olivetti E, Griffo R M, Rendine S, Amoroso A, Barbanti M, Caruso C, Conighi C, Conte R, Favoino B
Abstract excerpt
Human histocompatibility (HLA) gene frequencies were studied in the Italian population. A random sample of healthy individuals born in several Italian regions and provinces was studied to estimate HLA-A, -B, -C and -DR gene frequencies using the maximum likelihood method. The goodness of fit to Hardy-Weinberg proportions was evaluated by the likelihood ratio statistics. Different Italian regions and provinces...
Topics
- Alleles
- Gene Frequency
- Genetic Variation
- HLA Antigens
- Humans
- Italy
- Random Allocation
- Statistics as Topic
