Article
The contribution of inherited factors to the clinicopathological features and behavior of breast cancer.
Journal of mammary gland biology and neoplasia - 1 Oct 2001
Foulkes W D, Rosenblatt J, Chappuis P O
Abstract excerpt
This review is focused on genetic factors that may influence the development and/or appearance of breast cancer metastases. Over the last decade there have been significant advances in the understanding of genetic predisposition to breast cancer. The first breast cancer predisposing gene to be identified was TP53, and this was followed over the next 5 years by two more genes, BRCA1 and BRCA2, which from a...
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