Article
Various bacterial pathogens and symbionts infect the amoeba Dictyostelium discoideum.
International journal of medical microbiology : IJMM - 1 Mar 2002
Skriwan Carina, Fajardo Marcela, Hägele Sonja, Horn Matthias, Wagner Michael, Michel Rolf, Krohne Georg, Schleicher Michael, Hacker Jörg, Steinert Michael
Abstract excerpt
The haploid soil amoeba Dictyostelium discoideum is a suitable model organism to study host-pathogen interactions with Legionella pneumophila. In this study we show that D. discoideum AX2 is also susceptible to infection with other important human pathogens and obligate intracellular symbionts. Infection assays demonstrated that Legionella-like amoebal pathogens (LLAP K62), Mycobacterium avium and the obligate...
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