Article
Impact of polymorphisms of human beta-adrenergic receptor gene on changes in height during growth hormone treatment.
Endocrine journal - 1 Feb 2002
Matsuoka Hisafumi, Iwama Saika, Miura Naoko, Ikezaki Ayako, Sugihara Shigetaka
Abstract excerpt
The aim of this study was to investigate the occurrence of polymorphisms of the beta-adrenergic receptor gene in short children and to evaluate the possible influence of the polymorphisms on changes in height and obesity index in response to GH treatment. Of the 75 children enrolled in the study, 40 completed at least 5 years of GH treatment. The genotype distribution of the beta2 and 3-adrenergic receptor...
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