Pheochromocytoma — Death of an Axiom

Abstract excerpt

Medical students often learn axioms in order to remember the key features of a disorder. The “rule of 10” used to describe pheochromocytomas is a good example: 10 percent are extraadrenal, and of those, 10 percent are extraabdominal; 10 percent are malignant; 10 percent are found in patients who do not have hypertension; and finally, 10 percent are hereditary.1 Familial pheochromocytoma is inherited as an...

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