Article
Visualization of Lymphotoxin-β and Lymphotoxin-β Receptor Expression in Mouse Embryos
1 May 2002
Abstract excerpt
The heteromeric lymphotoxin alphabeta ligand (LT) binds to the LTbeta receptor (LTbetaR) and provides an essential trigger for lymph node (LN) development. LTbetaR signaling is also critical for the emergence of pathological ectopic lymph node-like structures and the maintenance of an organized splenic white pulp. To better understand the role of LT in development, the expression patterns of LTbeta and LTbetaR...
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