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Article

Role of p50/CDC37 in Hepadnavirus Assembly and Replication

1 Jul 2002

Abstract excerpt

The cellular chaperone Hsp90 has been shown to associate with the reverse transcriptase (RT) of the duck hepatitis B virus and is required for RT functions. However, the molecular basis for the specific interaction between the RT and Hsp90 remains unknown. Comparison of protein compositional properties suggests that the RT is highly related to the protein kinase c-Raf, which interacts with Hsp90 via the...

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PMID: 11986322
DOI: 10.1074/jbc.m202198200

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