Article
Intron evolution as a population-genetic process.
Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002
Lynch Michael
Abstract excerpt
Debate over the mechanisms responsible for the phylogenetic and genomic distribution of introns has proceeded largely without consideration of the population-genetic forces influencing the establishment and retention of novel genetic elements. However, a simple model incorporating random genetic drift and weak mutation pressure against intron-containing alleles yields predictions consistent with a diversity of...
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