Article
Microvascular endothelial cells differ in basal and hypoxia-regulated expression of angiogenic factors and their receptors.
Microvascular research - 1 May 2002
Tscheudschilsuren Gerelsul, Aust Gabriela, Nieber Karen, Schilling Nicole, Spanel-Borowski Katharina
Abstract excerpt
Phenotypically and functionally different types of microvascular endothelial cells (MVECs) derived from the developing corpus luteum were isolated and characterized by our group. We investigated whether these cytokeratin-positive (CK+) and cytokeratin-negative (CK-) MVECs differed in the expression of angiogenic factors and their regulation under hypoxia. Using quantitative RT-PCR, VEGF and its receptors, Flk-1...
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