Article
Role of human leukocyte antigen phenotype and exposure in development of occupational asthma.
Current opinion in allergy and clinical immunology - 1 Apr 2001
Taylor A N
Abstract excerpt
Studies of factory workforces in the past decade, exposed to both inhaled protein allergens (e.g. enzymes) and low molecular weight sensitisers (e.g. acid anhydrides), have provided consistent evidence of exposure-response relationships for both sensitisation (IgE production) and asthma. The development of molecular techniques has allowed investigation of candidate gene, in particular HLA Class 2 alleles, as risk...
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