Article
[Restricted usage of repertoire of T-cell receptor V beta in Chinese asthmatics].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Feb 2002
Guo Xuejun, Li Weijie, Deng Weiwu, Ni Peihua, Yu Shanchang, Li Yunzhu, Zhang Hongxi
Abstract excerpt
OBJECTIVE: To investigate the association of restricted usage of repertoire of T cell receptor V beta (TCR V beta) with asthma. METHODS: In 36 Chinese asthmatics, peripheral blood TCR V beta was studied by means of fluorescein-labeled RT-PCR as well as genescan and genotype software analysis. The clonality of the predominant usage T cell receptors was analyzed by denaturing gel electrophoresis and single strand...
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