Article
Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels.
Genetics, selection, evolution : GSE - 1 Jan 2000
Buchanan Fiona C, Fitzsimmons Carolyn J, Van Kessel Andrew G, Thue Tracey D, Winkelman-Sim Dianne C, Schmutz Sheila M
Abstract excerpt
Previously, we have shown that alleles of the BM1500 microsatellite, located 3.6 kb downstream of the leptin gene in cattle, were associated with carcass fat measures in a population of 154 unrelated beef bulls. Subsequently, a cytosine (C) to thymine (T) transition that encoded an amino acid change of an arginine to a cysteine was identified in exon 2 of the leptin gene. A PCR-RFLP was designed and allele...
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