[Cancer, what is it?].

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Article

[Cancer, what is it?].

Nederlands tijdschrift voor tandheelkunde - 1 Sept 1996

de Mulder P H

Abstract excerpt

Cancer is characterized by the independent growth of cells based on a series of genetic defects. These include changes in proto-oncogenes and tumor suppressor-genes and are based on both pre-existent and acquired alterations in the genome of the cell, caused by exogenous and endogenous factors. The development of cancer is not dependent on a single genetic hit, but requires a series of subsequent alterations. A...

Topics

DNA, Neoplasm
Disease Progression
Genes, Tumor Suppressor
Humans
Mutation
Neoplasm Metastasis
Neoplasms
Proto-Oncogenes

Source

Open in PubMed

Identifiers

PMID: 11921917

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