Rapid interphase analysis for prenatal diagnosis of translocation carriers using subtelomeric probes

Abstract excerpt

Interphase fluorescence in situ hybridization (FISH) has become an accepted laboratory technique for the rapid and preliminary prenatal assessment of chromosome aneuploidy. The introduction of subtelomeric FISH probes now allows for the molecular-cytogenetic analysis of terminal chromosome rearrangements. In a prospective study, we examined the prenatal use of subtelomeric probes on interphase cells to rapidly...

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• Share to Chromosomal and Genetic Variations
• Share to Genomic variations and chromosomal abnormalities
• Share to Prenatal Screening and Diagnostics