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Article

Case-specific, breakpoint-spanning DNA probes for analysis of single interphase cells.

Genetic testing - 1 Jan 2000

Lersch R A, Fung J, Munné S, Pedersen R A, Weier H U

Abstract excerpt

Balanced reciprocal translocations are known to interfere with homolog pairing in meiosis. Many individuals carrying such chromosomal abnormalities suffer from reduced fertility or spontaneous abortions and seek help in the form of assisted reproductive technology. Although most translocations are relatively easy to detect in metaphase cells, the majority of embryonic cells biopsied in the course of in vitro...

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PMID: 11142758
DOI: 10.1089/10906570050501498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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